基因名称(Gene Name)
RND3 ARHE RHO8 RHOE
蛋白名称
Rho-related GTP-binding protein RhoE (Protein MemB) (Rho family GTPase 3) (Rho-related GTP-binding protein Rho8) (Rnd3)
免疫原
Synthesized peptide derived from human protein . at AA range: 150-230
特异性
RND3 Monoclonal Antibody detects endogenous levels of protein.
组成
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
背景
This gene encodes a protein which is a member of the small GTPase protein superfamily. The encoded protein binds only GTP but has no GTPase activity, and appears to act as a negative regulator of cytoskeletal organization leading to loss of adhesion. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Dec 2011],
功能
function:Binds GTP but lacks intrinsic GTPase activity and is resistant to Rho-specific GTPase-activating proteins.,similarity:Belongs to the small GTPase superfamily. Rho family.,subunit:Binds ROCK1 (By similarity). Interacts with UBXD5.,tissue specificity:Ubiquitous.,
