基因名称(Gene Name)
RARRES3 RIG1 TIG3
蛋白名称
Retinoic acid receptor responder protein 3 (EC 3.1.1.-) (RAR-responsive protein TIG3) (Retinoid-inducible gene 1 protein) (Tazarotene-induced gene 3 protein)
免疫原
Synthesized peptide derived from human protein . at AA range: 80-160
特异性
TIG3 Monoclonal Antibody detects endogenous levels of protein.
组成
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
背景
Retinoids exert biologic effects such as potent growth inhibitory and cell differentiation activities and are used in the treatment of hyperproliferative dermatological diseases. These effects are mediated by specific nuclear receptor proteins that are members of the steroid and thyroid hormone receptor superfamily of transcriptional regulators. RARRES1, RARRES2, and RARRES3 are genes whose expression is upregulated by the synthetic retinoid tazarotene. RARRES3 is thought act as a tumor suppressor or growth regulator. [provided by RefSeq, Jul 2008],
功能
function:May be a growth regulator that mediates some of the growth suppressive effects of retinoids.,induction:By tazarotene.,similarity:Belongs to the H-rev107 family.,tissue specificity:Expressed in many tissues. Not expressed in heart, brain, and testis.,
