基因名称(Gene Name)
RAD51AP1 PIR51
蛋白名称
RAD51-associated protein 1 (RAD51-interacting protein)
免疫原
Synthesized peptide derived from human protein . at AA range: 90-170
特异性
R51A1 Monoclonal Antibody detects endogenous levels of protein.
组成
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
背景
alternative products:Additional isoforms seem to exist,function:May participate in a common DNA damage response pathway associated with the activation of homologous recombination and double-strand break repair. Binds to single and double stranded DNA, and is caMABle of aggregating DNA. Also binds RNA.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,subcellular location:Colocalizes with RAD51 to multiple nuclear foci.,subunit:Isoform 2 interacts with RAD51.,tissue specificity:Highly expressed in testis and thymus. Lower levels in colon and small intestine. Little or no expression in spleen, prostate, ovary and peripheral blood leukocytes.,
功能
alternative products:Additional isoforms seem to exist,function:May participate in a common DNA damage response pathway associated with the activation of homologous recombination and double-strand break repair. Binds to single and double stranded DNA, and is caMABle of aggregating DNA. Also binds RNA.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,subcellular location:Colocalizes with RAD51 to multiple nuclear foci.,subunit:Isoform 2 interacts with RAD51.,tissue specificity:Highly expressed in testis and thymus. Lower levels in colon and small intestine. Little or no expression in spleen, prostate, ovary and peripheral blood leukocytes.,
