基因名称(Gene Name)
S100A14 S100A15
蛋白名称
Protein S100-A14 (S100 calcium-binding protein A14) (S114)
免疫原
Synthesized peptide derived from human protein . at AA range: 30-110
特异性
S10AE Monoclonal Antibody detects endogenous levels of protein.
组成
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
背景
This gene encodes a member of the S100 protein family which contains an EF-hand motif and binds calcium. The gene is located in a cluster of S100 genes on chromosome 1. Levels of the encoded protein have been found to be lower in cancerous tissue and associated with metastasis suggesting a tumor suppressor function (PMID: 19956863, 19351828). [provided by RefSeq, Dec 2011],
功能
similarity:Belongs to the S-100 family.,similarity:Contains 2 EF-hand domains.,tissue specificity:Expressed at highest levels in colon and at moderate levels in thymus, kidney, liver, small intestine, and lung. Low expression in heart and no expression is seen in brain, skeletal muscle, spleen, placenta and peripheral blood leukocytes.,
