基因名称(Gene Name)
PPME1 PME1 PP2593 PRO0750
蛋白名称
Protein phosphatase methylesterase 1 (PME-1) (EC 3.1.1.89)
免疫原
Synthesized peptide derived from human protein . at AA range: 220-300
特异性
PPME1 Monoclonal Antibody detects endogenous levels of protein.
组成
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
背景
This gene encodes a protein phosphatase methylesterase localized to the nucleus. The encoded protein acts on the protein phosphatase-2A catalytic subunit and supports the ERK pathway through dephosphorylation of regulatory proteins. It plays a role in malignant glioma progression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2012],
功能
function:Demethylates proteins that have been reversibly carboxymethylated. Demethylates PPP2CB (in vitro).,sequence caution:Wrong choice of CDS.,similarity:Belongs to the AB hydrolase superfamily.,subunit:Binds PPP2CB.,
