基因名称(Gene Name)
NUDCD3 KIAA1068
蛋白名称
NudC domain-containing protein 3
免疫原
Synthesized peptide derived from human protein . at AA range: 30-110
特异性
NUDC3 Monoclonal Antibody detects endogenous levels of protein.
组成
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
背景
The product of this gene functions to maintain the stability of dynein intermediate chain. Depletion of this gene product results in aggregation and degradation of dynein intermediate chain, mislocalization of the dynein complex from kinetochores, spindle microtubules, and spindle poles, and loss of gamma-tubulin from spindle poles. The protein localizes to the Golgi apparatus during interphase, and levels of the protein increase after the G1/S transition. [provided by RefSeq, Jul 2008],
功能
PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 CS domain.,
