基因名称(Gene Name)
NLGN2 KIAA1366
免疫原
Synthesized peptide derived from human protein . at AA range: 310-390
特异性
NLGN2 Monoclonal Antibody detects endogenous levels of protein.
组成
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
背景
This gene encodes a member of a family of neuronal cell surface proteins. Members of this family may act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses. [provided by RefSeq, Jul 2008],
功能
function:Neuronal cell surface protein thought to be involved in cell-cell-interactions by forming intercellular junctions through binding to beta-neurexins. Seems to play role in formation or maintenance of synaptic junctions. In vitro, triggers the de novo formation of presynaptic structures.,similarity:Belongs to the type-B carboxylesterase/lipase family.,subunit:Interacts with neurexin 1-beta, neurexin 2-beta and neurexin 3-beta. Interacts with INADL (By similarity). Probably interacts through its C-terminus with DLG4 third PDZ domain.,