基因名称(Gene Name)
NGDN C14orf120
蛋白名称
Neuroguidin (EIF4E-binding protein)
免疫原
Synthesized peptide derived from human protein . at AA range: 240-320
特异性
NGDN Monoclonal Antibody detects endogenous levels of protein.
组成
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
背景
Neuroguidin is an EIF4E (MIM 133440)-binding protein that interacts with CPEB (MIM 607342) and functions as a translational regulatory protein during development of the vertebrate nervous system (Jung et al., 2006 [PubMed 16705177]).[supplied by OMIM, Mar 2008],
功能
function:Involved in the translational repression of cytoplasmic polyadenylation element (CPE)-containing mRNAs.,similarity:Belongs to the SAS10 family.,subcellular location:Detected in axons, dendrites and filopodia. Colocalized with EIF4E in neurites.,subunit:Interacts with CPEB1 and EIF4E.,
