基因名称(Gene Name)
NRXN3 C14orf60 KIAA0743
蛋白名称
Neurexin-3-alpha (Neurexin III-alpha)
免疫原
Synthesized peptide derived from human protein . at AA range: 480-560
特异性
NRX3A Monoclonal Antibody detects endogenous levels of protein.
组成
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
背景
alternative products:A number of isoforms, alpha-type (AC Q9Y4C0) and beta-type (shown here), are produced by alternative promoter usage. Beta-type isoforms differ from alpha-type isoforms in their N-terminus,alternative products:A number of isoforms, alpha-type (shown here) and beta-type (AC Q9HDB5), are produced by alternative promoter usage. Beta-type isoforms differ from alpha-type isoforms in their N-terminus. Additional isoforms produced by alternative splicing seem to exist,function:Neuronal cell surface protein that may be involved in cell recognition and cell adhesion.,function:Neuronal cell surface protein that may be involved in cell recognition and cell adhesion. May mediate intracellular signaling.,similarity:Belongs to the neurexin family.,similarity:Contains 1 laminin G-like domain.,similarity:Contains 3 EGF-like domains.,similarity:Contains 6 laminin G-like domains.,subunit:The cytoplasmic C-terminal region binds to CASK (By similarity). Binds to neuroligins NLGN1, NLGN2 and NLGN3.,subunit:The laminin G-like domain 2 binds to NXPH1. Specific isoforms bind to alpha-dystroglycan. The cytoplasmic C-terminal region binds to CASK.,tissue specificity:Predominantly expressed in brain.,
功能
alternative products:A number of isoforms, alpha-type (AC Q9Y4C0) and beta-type (shown here), are produced by alternative promoter usage. Beta-type isoforms differ from alpha-type isoforms in their N-terminus,alternative products:A number of isoforms, alpha-type (shown here) and beta-type (AC Q9HDB5), are produced by alternative promoter usage. Beta-type isoforms differ from alpha-type isoforms in their N-terminus. Additional isoforms produced by alternative splicing seem to exist,function:Neuronal cell surface protein that may be involved in cell recognition and cell adhesion.,function:Neuronal cell surface protein that may be involved in cell recognition and cell adhesion. May mediate intracellular signaling.,similarity:Belongs to the neurexin family.,similarity:Contains 1 laminin G-like domain.,similarity:Contains 3 EGF-like domains.,similarity:Contains 6 laminin G-like domains.,subun
