基因名称(Gene Name)
MYO5B KIAA1119
蛋白名称
Unconventional myosin-Vb
免疫原
Synthesized peptide derived from human protein . at AA range: 1120-1200
特异性
MYO5B Monoclonal Antibody detects endogenous levels of protein.
组成
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
背景
The protein encoded by this gene, together with other proteins, may be involved in plasma membrane recycling. Mutations in this gene are associated with microvillous inclusion disease. [provided by RefSeq, Sep 2009],
功能
disease:Defects in MYO5B are a cause of microvillus inclusion disease (MVID) [MIM:251850]. MVID is characterized by onset of intractable life-threatening watery diarrhea during infancy. Two forms are recognized: early-onset MVID with diarrhea beginning in the neonatal period, and late-onset, with first symptoms appearing after 3 or 4 months of life.,similarity:Contains 1 dilute domain.,similarity:Contains 1 myosin head-like domain.,similarity:Contains 6 IQ domains.,subunit:Interacts with RAB11FIP2.,
