基因名称(Gene Name)
CDHR5 MUCDHL MUPCDH UNQ2781/PRO7168
蛋白名称
Cadherin-related family member 5 (Mu-protocadherin) (Mucin and cadherin-like protein)
免疫原
Synthesized peptide derived from human protein . at AA range: 80-160
特异性
CDHR5 Monoclonal Antibody detects endogenous levels of protein.
组成
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
背景
cadherin related family member 5(CDHR5) Homo sapiens This gene is a novel mucin-like gene that is a member of the cadherin superfamily. While encoding nonpolymorphic tandem repeats rich in proline, serine and threonine similar to mucin proteins, the gene also contains sequence encoding calcium-binding motifs found in all cadherins. The role of the hybrid extracellular region and the specific function of this protein have not yet been determined. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jan 2010],
功能
function:Acts as a calcium-dependent cell adhesion protein.,PTM:N- and O-glycosylated.,similarity:Contains 4 cadherin domains.,tissue specificity:Highest expression in kidney, liver, colon and small intestine. In kidney, expressed apically along brush border of proximal convoluted tubule but not in cortical collecting ducts. Isoform 1 is expressed primarily in adult small intestine and colon. Isoform 2 is highly expressed in fetal liver.,
