基因名称(Gene Name)
LRP4 KIAA0816 LRP10 MEGF7
蛋白名称
Low-density lipoprotein receptor-related protein 4 (LRP-4) (Multiple epidermal growth factor-like domains 7)
免疫原
Synthesized peptide derived from human protein . at AA range: 290-370
特异性
LRP4 Monoclonal Antibody detects endogenous levels of protein.
组成
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
背景
This gene encodes a member of the low-density lipoprotein receptor-related protein family. The encoded protein may be a regulator of Wnt signaling. Mutations in this gene are associated with Cenani-Lenz syndrome. [provided by RefSeq, May 2010],
功能
function:Potential cell surface endocytic receptor, which binds and internalizes extracellular ligands for degradation by lysosomes.,similarity:Belongs to the LDLR family.,similarity:Contains 20 LDL-receptor class B repeats.,similarity:Contains 3 EGF-like domains.,similarity:Contains 8 LDL-receptor class A domains.,tissue specificity:Expressed in several regions of the brain.,
