基因名称(Gene Name)
DIRAS3 ARHI NOEY2 RHOI
蛋白名称
GTP-binding protein Di-Ras3 (Distinct subgroup of the Ras family member 3) (Rho-related GTP-binding protein RhoI)
免疫原
Synthesized peptide derived from part region of human protein
特异性
DIRA3 Monoclonal Antibody detects endogenous levels of protein.
组成
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
背景
This gene encodes a member of the ras superfamily. This gene is imprinted gene with monoallelic expression of the paternal allele which is associated with growth suppression. The encoded protein acts as a tumor suppressor whose function is abrogated in many ovarian and breast cancers. This protein may also play a role autophagy in certain cancer cells by regulating the autophagosome initiation complex. [provided by RefSeq, Nov 2015],
功能
online information:NOEY2 entry,similarity:Belongs to the small GTPase superfamily. Di-Ras family.,tissue specificity:Expressed in normal ovarian and breast epithelial cells but not in ovarian and breast cancers.,
