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货号: YP-mAb-05478
促销价:

产品介绍

反应种属
Human;Mouse
应用范围
WB
抗体类型
单克隆抗体
基因名称(Gene Name)
CLDN23
蛋白名称
Claudin-23
分子量(DA)
32kD
免疫原
Synthesized peptide derived from part region of human protein
特异性
CLD23 Monoclonal Antibody detects endogenous levels of protein.
组成
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
来源
Monoclonal, Mouse,IgG
稀释比例
WB 1:500-2000
纯化工艺
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
浓度
1 mg/ml
储存
-20°C/1 year
其他名称
背景
This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is expressed in germinal center B-cells, placenta and stomach as well as in colon tumor. This gene is down-regulated in intestinal type gastric cancer. [provided by RefSeq, Aug 2010],
功能
function:Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.,similarity:Belongs to the claudin family.,tissue specificity:Expressed in germinal center B-cells, placenta, stomach as well as in colon tumor.,

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