基因名称(Gene Name)
CRABP1 RBP5
蛋白名称
Cellular retinoic acid-binding protein 1 (Cellular retinoic acid-binding protein I) (CRABP-I)
免疫原
Synthesized peptide derived from part region of human protein
特异性
RABP1 Monoclonal Antibody detects endogenous levels of protein.
组成
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
背景
This gene encodes a specific binding protein for a vitamin A family member and is thought to play an important role in retinoic acid-mediated differentiation and proliferation processes. It is structurally similar to the cellular retinol-binding proteins, but binds only retinoic acid at specific sites within the nucleus, which may contribute to vitamin A-directed differentiation in epithelial tissue. [provided by RefSeq, Jul 2008],
功能
domain:Forms a beta-barrel structure that accommodates hydrophobic ligands in its interior.,function:Cytosolic CRABPs may regulate the access of retinoic acid to the nuclear retinoic acid receptors.,similarity:Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.,
