基因名称(Gene Name)
CDC42EP1 BORG5 CEP1 MSE55
蛋白名称
Cdc42 effector protein 1 (Binder of Rho GTPases 5) (Serum protein MSE55)
免疫原
Synthesized peptide derived from part region of human protein
特异性
BORG5 Monoclonal Antibody detects endogenous levels of protein.
组成
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
背景
CDC42 is a member of the Rho GTPase family that regulates multiple cellular activities, including actin polymerization. The protein encoded by this gene is a CDC42 binding protein that mediates actin cytoskeleton reorganization at the plasma membrane. This protein is secreted and is primarily found in bone marrow. [provided by RefSeq, Jul 2008],
功能
domain:The CRIB domain mediates interaction with CDC42.,function:Probably involved in the organization of the actin cytoskeleton. Induced membrane extensions in fibroblasts.,similarity:Belongs to the BORG/CEP family.,similarity:Contains 1 CRIB domain.,subunit:Interacts with RHOQ and CDC42, in a GTP-dependent manner.,tissue specificity:Endothelial and bone marrow stromal cells.,
