基因名称(Gene Name)
ANGPT4 ANG3 ANG4
蛋白名称
Angiopoietin-4 (ANG-4) (Angiopoietin-3) (ANG-3)
免疫原
Synthesized peptide derived from human protein . at AA range: 150-230
特异性
ANGP4 Monoclonal Antibody detects endogenous levels of protein.
组成
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
背景
Angiopoietins are proteins with important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. The mechanism by which they contribute to angiogenesis is thought to involve regulation of endothelial cell interactions with supporting perivascular cells. The protein encoded by this gene functions as an agonist and is an angiopoietin. [provided by RefSeq, Jul 2008],
功能
caution:Was originally (PubMed:10218486) called angiopoietin-3.,function:Binds to tyrosine-protein kinase receptor TIE2 and activates it.,similarity:Contains 1 fibrinogen C-terminal domain.,tissue specificity:Highly expressed in the lung with much lower levels found in other tissues.,
