基因名称(Gene Name)
LPCAT4 AGPAT7 AYTL3 LPEAT2
蛋白名称
Lysophospholipid acyltransferase LPCAT4 (EC 2.3.1.-) (1-acylglycerol-3-phosphate O-acyltransferase 7) (1-AGP acyltransferase 7) (1-AGPAT 7) (Acyltransferase-like 3) (Lysophosphatidylcholine acyltransf
免疫原
Synthesized peptide derived from human protein . at AA range: 300-380
特异性
LPCT4 Monoclonal Antibody detects endogenous levels of protein.
组成
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
背景
Members of the 1-acylglycerol-3-phosphate O-acyltransferase (EC 2.3.1.51) family, such as AGPAT7, catalyze the conversion of lysophosphatidic acid (LPA) to phosphatidic acid (PA), a precursor in the biosynthesis of all glycerolipids. Both LPA and PA are involved in signal transduction (Ye et al., 2005 [PubMed 16243729]).[supplied by OMIM, May 2008],
功能
caution:Was originally (PubMed:16243729) thought to be a lysophosphatidic acid acyltransferase based on sequence similarity but the mouse ortholog has been shown to be a lysophosphatidylcholine acyltransferase.,function:Converts lysophosphatidylcholine (LPC) to phosphatidycholine in the presence of acyl-CoA.,pathway:Lipid metabolism; phospholipid metabolism.,similarity:Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.,tissue specificity:Widely expressed. Expressed in uterus, thymus, pancreas, skeletal muscle, bladder, stomach, lung and testis.,
