基因名称(Gene Name)
VEZF1 DB1 ZNF161
蛋白名称
Vascular endothelial zinc finger 1 (Putative transcription factor DB1) (Zinc finger protein 161)
免疫原
Synthesized peptide derived from human protein . at AA range: 1-80
特异性
VEZF1 Monoclonal Antibody detects endogenous levels of protein.
组成
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
背景
Transcriptional regulatory proteins containing tandemly repeated zinc finger domains are thought to be involved in both normal and abnormal cellular proliferation and differentiation. ZNF161 is a C2H2-type zinc finger protein (Koyano-Nakagawa et al., 1994 [PubMed 8035792]). See MIM 603971 for general information on zinc finger proteins.[supplied by OMIM, Sep 2008],
功能
function:Possible transcription factor. Specifically binds to the CT/GC-rich region of the interleukin-3 promoter and mediates tax transactivation of IL-3.,similarity:Belongs to the krueppel C2H2-type zinc-finger protein family.,similarity:Contains 6 C2H2-type zinc fingers.,subunit:Interacts with ARHGAP22.,tissue specificity:Ubiquitously expressed. Highest levels in skeletal muscle and kidney.,
