基因名称(Gene Name)
TRIM35 HLS5 KIAA1098
蛋白名称
Tripartite motif-containing protein 35 (Hemopoietic lineage switch protein 5)
免疫原
Synthesized peptide derived from human protein . at AA range: 320-400
特异性
TRI35 Monoclonal Antibody detects endogenous levels of protein.
组成
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
背景
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The function of this protein has not been identified. [provided by RefSeq, Jul 2008],
功能
domain:The RING finger domain and the coiled-coil region are required for the apoptosis-inducing activity.,function:May play a role as a tumor suppressor. Implicated in the cell death mechanism.,similarity:Belongs to the TRIM/RBCC family.,similarity:Contains 1 B box-type zinc finger.,similarity:Contains 1 B30.2/SPRY domain.,similarity:Contains 1 RING-type zinc finger.,subcellular location:Found predominantly in cytoplasm with a granular distribution. Found in punctuate nuclear bodies.,
