蛋白名称
Tumor protein D53 (hD53) (Tumor protein D52-like 1)
免疫原
Synthesized peptide derived from human protein . at AA range: 30-110
特异性
TPD53 Monoclonal Antibody detects endogenous levels of protein.
组成
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
背景
This gene encodes a member of a family of proteins that contain coiled-coil domains and may form hetero- or homomers. The encoded protein is involved in cell proliferation and calcium signaling. It also interacts with the mitogen-activated protein kinase kinase kinase 5 (MAP3K5/ASK1) and positively regulates MAP3K5-induced apoptosis. Multiple alternatively spliced transcript variants have been observed. [provided by RefSeq, Jan 2016],
功能
similarity:Belongs to the TPD52 family.,subunit:Forms homodimer or heterodimer with other members of the family.,