蛋白名称
Metal regulatory transcription factor 1 (MRE-binding transcription factor) (Transcription factor MTF-1)
免疫原
Synthesized peptide derived from human protein . at AA range: 260-340
特异性
MTF1 Monoclonal Antibody detects endogenous levels of protein.
组成
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
背景
This gene encodes a transcription factor that induces expression of metallothioneins and other genes involved in metal homeostasis in response to heavy metals such as cadmium, zinc, copper, and silver. The protein is a nucleocytoplasmic shuttling protein that accumulates in the nucleus upon heavy metal exposure and binds to promoters containing a metal-responsive element (MRE). [provided by RefSeq, Jul 2008],
功能
function:Activates the metallothionein I promoter. Binds to the metal responsive element (MRE).,similarity:Contains 6 C2H2-type zinc fingers.,
