基因名称(Gene Name)
CSTA STF1 STFA
蛋白名称
Cystatin-A (Cystatin-AS) (Stefin-A)
免疫原
Synthetic peptide from human protein at AA range: 60-98
特异性
The antibody detects endogenous Cystatin A
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
其他名称
Cystatin-A (Cystatin-AS;Stefin-A)
背景
The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins, and kininogens. This gene encodes a stefin that functions as a cysteine protease inhibitor, forming tight complexes with papain and the cathepsins B, H, and L. The protein is one of the precursor proteins of cornified cell envelope in keratinocytes and plays a role in epidermal development and maintenance. Stefins have been proposed as prognostic and diagnostic tools for cancer. [provided by RefSeq, Jul 2008],
功能
function:This is an intracellular thiol proteinase inhibitor.,similarity:Belongs to the cystatin family.,
