蛋白名称
HSPB1-associated protein 1
免疫原
The antiserum was produced against synthesized peptide derived from the Internal region of human HSPBAP1. AA range:321-370
特异性
HSPBAP1 Monoclonal Antibody detects endogenous levels of HSPBAP1 protein.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
其他名称
HSPBAP1; PASS1; HSPB1-associated protein 1; 27 kDa heat shock protein-associated protein 1; Protein associated with small stress protein 1
背景
This gene encodes a protein that binds to one of the small heat shock proteins, specifically hsp27. Hsp27 is involved with cell growth and differentiation. This encoded protein was found to be abnormally expressed in patients with intractable epilepsy, although how brain function is affected remains unknown. [provided by RefSeq, Sep 2011],
功能
disease:A chromosomal aberration involving HSPBAP1 is found in familial renal cell carcinoma 1 (RCC1) [MIM:144700]. Translocation t(2;3)(q35;q21) with the putative pseudogene DIRC3. Produces an hybrid mRNA encoding a truncated HSPBAP1 lacking the first 36 amino acids.,function:May play a role in cellular stress response.,similarity:Contains 1 JmjC domain.,subunit:Interacts with CRYAB and HSPB1.,tissue specificity:Widely expressed.,
