蛋白名称
Alpha-1,4-N-acetylglucosaminyltransferase
免疫原
The antiserum was produced against synthesized peptide derived from human A4GNT. AA range:31-80
特异性
α4Gn-T Monoclonal Antibody detects endogenous levels of α4Gn-T protein.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
其他名称
A4GNT; Alpha-1; 4-N-acetylglucosaminyltransferase; Alpha4GnT
背景
This gene encodes a protein from the glycosyltransferase 32 family. The enzyme catalyzes the transfer of N-acetylglucosamine (GlcNAc) to core 2 branched O-glycans. It forms a unique glycan, GlcNAcalpha1-->4Galbeta-->R and is largely associated with the Golgi apparatus membrane. [provided by RefSeq, Jul 2008],
功能
domain:The conserved DXD motif is involved in enzyme activity.,function:Necessary for the synthesis of type III mucin. Catalyzes the transfer of N-acetylglucosamine (GlcNAc) to core 2 branched O-glycans.,online information:Alpha-1,4-N-acetylglucosaminyltransferase,online information:GlycoGene database,pathway:Protein modification; protein glycosylation.,similarity:Belongs to the glycosyltransferase 32 family.,tissue specificity:Detected in stomach and pancreas.,
