免疫原
The antiserum was produced against synthesized peptide derived from human SFXN4. AA range:1-50
特异性
Sideroflexin-4 Monoclonal Antibody detects endogenous levels of Sideroflexin-4 protein.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
其他名称
SFXN4; BCRM1; Sideroflexin-4; Breast cancer resistance marker 1
背景
This gene encodes a member of the sideroflexin family. The encoded protein is a transmembrane protein of the inner mitochondrial membrane, and is required for mitochondrial respiratory homeostasis and erythropoiesis. Mutations in this gene are associated with mitochondriopathy and macrocytic anemia. Alternatively spliced transcript variants have been found in this gene. [provided by RefSeq, Jan 2014],
功能
function:Potential iron transporter.,similarity:Belongs to the sideroflexin family.,