蛋白名称
Phosphatidylinositol transfer protein beta isoform
免疫原
The antiserum was produced against synthesized peptide derived from human PITPNB. AA range:20-69
特异性
PITPβ Monoclonal Antibody detects endogenous levels of PITPβ protein.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
其他名称
PITPNB; Phosphatidylinositol transfer protein beta isoform; PI-TP-beta; PtdIns transfer protein beta; PtdInsTP beta
背景
This gene encodes a cytoplasmic protein that catalyzes the transfer of phosphatidylinositol and phosphatidylcholine between membranes. This transfer activity is required for COPI complex-mediated retrograde transport from the Golgi apparatus to the endoplasmic reticulum. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2013],
功能
function:Catalyzes the transfer of PtdIns and phosphatidylcholine between membranes.,PTM:Constitutive phosphorylation of Ser-262 has no effect on phospholipid transfer activity but is required for Golgi targeting.,similarity:Belongs to the PtdIns transfer protein family. Class I subfamily.,tissue specificity:Widely expressed in various tissues including brain.,
