蛋白名称
Protein phosphatase 1 regulatory subunit 16A
免疫原
The antiserum was produced against synthesized peptide derived from human PPP1R16A. AA range:362-411
特异性
MYPT3 Monoclonal Antibody detects endogenous levels of MYPT3 protein.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
其他名称
PPP1R16A; MYPT3; Protein phosphatase 1 regulatory subunit 16A; Myosin phosphatase-targeting subunit 3
背景
Myosin light chain kinase and phosphatase (MLCP) complexes control the phosphorylation states of regulatory myosin light chains, which is crucial for muscle and intracellular movement. MLCPs typically contain a catalytic protein phosphatase 1 (PP1c) subunit, a myosin phosphatase targeting (MYPT) subunit, and another smaller subunit. The protein encoded by this gene represents an MYPT subunit, which is responsible for directing PP1c to its intended targets. However, while other MYPTs result in PP1c activation after becoming phosphorylated, the encoded protein is phosphorylated by protein kinase A and then inhibits the catalytic activity of PP1c. [provided by RefSeq, Jul 2016],
功能
function:Inhibits protein phosphatase 1 activity toward phosphorylase, myosin light chain and myosin substrates.,sequence caution:Cloning artifact.,similarity:Contains 5 ANK repeats.,subunit:Binds PP1.,
