免疫原
The antiserum was produced against synthesized peptide derived from human NADAP. AA range:421-470
特异性
Kanadaptin Monoclonal Antibody detects endogenous levels of Kanadaptin protein.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
Western Blot: 1/500 - 1/2000
纯化工艺
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
其他名称
SLC4A1AP; HLC3; Kanadaptin; Human lung cancer oncogene 3 protein; HLC-3; Kidney anion exchanger adapter protein; Solute carrier family 4 anion exchanger member 1 adapter protein
背景
caution:PubMed:15764369 initially suggested a role in targeting SLC4A1 (kidney anion exchanger 1) to the plasma membrane; it does not seem to do so as it does not interact with SLC4A1 and has no effect on SLC4A1 trafficking.,online information:Band 3 entry,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 FHA domain.,subcellular location:Mainly nuclear. Small amounts are found in the cytoplasm.,tissue specificity:Ubiquitously expressed.,
功能
caution:PubMed:15764369 initially suggested a role in targeting SLC4A1 (kidney anion exchanger 1) to the plasma membrane; it does not seem to do so as it does not interact with SLC4A1 and has no effect on SLC4A1 trafficking.,online information:Band 3 entry,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 FHA domain.,subcellular location:Mainly nuclear. Small amounts are found in the cytoplasm.,tissue specificity:Ubiquitously expressed.,
