蛋白名称
Heat shock protein 105 kDa
免疫原
The antiserum was produced against synthesized peptide derived from human HSP105. AA range:791-840
特异性
HSP105 Monoclonal Antibody detects endogenous levels of HSP105 protein.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
Western Blot: 1/500 - 1/2000
纯化工艺
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
其他名称
HSPH1; HSP105; HSP110; KIAA0201; Heat shock protein 105 kDa; Antigen NY-CO-25; Heat shock 110 kDa protein
背景
function:Prevents the aggregation of denatured proteins in cells under severe stress, on which the ATP levels decrease markedly. Inhibits HSPA8/HSC70 ATPase and chaperone activities.,PTM:Phosphorylation on Ser-509 may be important for regulation of the HSPA8/HSC70 chaperone activity.,similarity:Belongs to the heat shock protein 70 family.,subunit:Interacts with HSPA8/HSC70.,tissue specificity:Highly expressed in testis. Present at lower levels in most brain regions, except cerebellum. Overexpressed in cancer cells.,
功能
function:Prevents the aggregation of denatured proteins in cells under severe stress, on which the ATP levels decrease markedly. Inhibits HSPA8/HSC70 ATPase and chaperone activities.,PTM:Phosphorylation on Ser-509 may be important for regulation of the HSPA8/HSC70 chaperone activity.,similarity:Belongs to the heat shock protein 70 family.,subunit:Interacts with HSPA8/HSC70.,tissue specificity:Highly expressed in testis. Present at lower levels in most brain regions, except cerebellum. Overexpressed in cancer cells.,
