免疫原
The antiserum was produced against synthesized peptide derived from human GALK1. AA range:1-50
特异性
GALK1 Monoclonal Antibody detects endogenous levels of GALK1 protein.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
Western Blot: 1/500 - 1/2000
纯化工艺
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
其他名称
GALK1; GALK; Galactokinase; Galactose kinase
背景
Galactokinase is a major enzyme for the metabolism of galactose and its deficiency causes congenital cataracts during infancy and presenile cataracts in the adult population. [provided by RefSeq, Jul 2008],
功能
catalytic activity:ATP + D-galactose = ADP + alpha-D-galactose 1-phosphate.,disease:Defects in GALK1 are the cause of galactosemia II [MIM:230200]. It is an autosomal recessive deficiency characterized by congenital cataracts during infancy and presenile cataracts in the adult population. The cataracts are secondary to accumulation of galactitol in the lenses.,function:Major enzyme for galactose metabolism.,pathway:Carbohydrate metabolism; galactose metabolism.,similarity:Belongs to the GHMP kinase family.,similarity:Belongs to the GHMP kinase family. GalK subfamily.,
