蛋白名称
THO complex subunit 5 homolog
免疫原
The antiserum was produced against synthesized peptide derived from human THOC5. AA range:561-610
特异性
FMIP Monoclonal Antibody detects endogenous levels of FMIP protein.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
其他名称
THOC5; C22orf19; KIAA0983; THO complex subunit 5 homolog; Functional spliceosome-associated protein 79; fSAP79; NF2/meningioma region protein pK1.3; Placental protein 39.2; PP39.2; hTREX90
背景
function:May be involved in the differentiation of granulocytes and adipocytes.,PTM:Phosphorylated on tyrosine upon binding to activated CSF1R; which causes a dissociation of the two proteins. Phosphorylation on Ser-5 and/or Ser-6 is required for nuclear export. Phosphorylated on Thr-328 in insulin-stimulated adipocytes (By similarity). Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the THOC5 family.,subcellular location:Shuttles between nucleus and cytoplasm.,subunit:Interacts with phosphorylated CSF1R.,tissue specificity:Ubiquitously expressed.,
功能
function:May be involved in the differentiation of granulocytes and adipocytes.,PTM:Phosphorylated on tyrosine upon binding to activated CSF1R; which causes a dissociation of the two proteins. Phosphorylation on Ser-5 and/or Ser-6 is required for nuclear export. Phosphorylated on Thr-328 in insulin-stimulated adipocytes (By similarity). Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the THOC5 family.,subcellular location:Shuttles between nucleus and cytoplasm.,subunit:Interacts with phosphorylated CSF1R.,tissue specificity:Ubiquitously expressed.,
