蛋白名称
Segment polarity protein dishevelled homolog DVL-3
免疫原
The antiserum was produced against synthesized peptide derived from human DVL3. AA range:326-375
特异性
Dvl-3 Monoclonal Antibody detects endogenous levels of Dvl-3 protein.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
其他名称
DVL3; KIAA0208; Segment polarity protein dishevelled homolog DVL-3; Dishevelled-3; DSH homolog 3
背景
This gene is a member of a multi-gene family which shares strong similarity with the Drosophila dishevelled gene, dsh. The Drosophila dishevelled gene encodes a cytoplasmic phosphoprotein that regulates cell proliferation. [provided by RefSeq, Jul 2008],
功能
function:May play a role in the signal transduction pathway mediated by multiple Wnt genes.,similarity:Belongs to the DSH family.,similarity:Contains 1 DEP domain.,similarity:Contains 1 DIX domain.,similarity:Contains 1 PDZ (DHR) domain.,subunit:Interacts (via the PDZ domain) with the C-terminal regions of VANGL1 and VANGL2 (By similarity). Interacts (via the region containing both the PDZ and DEP domains) with LRRFIP2; the DIX domain may inhibit this interaction.,
