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Periphilin 1 Monoclonal Antibody

货号: YP-mAb-03169
促销价:

产品介绍

反应种属
Human;Mouse
应用范围
WB
抗体类型
单克隆抗体
基因名称(Gene Name)
PPHLN1
蛋白名称
Periphilin-1
分子量(DA)
53kD
免疫原
The antiserum was produced against synthesized peptide derived from human PPHLN. AA range:71-120
特异性
Periphilin 1 Monoclonal Antibody detects endogenous levels of Periphilin 1 protein.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源
Monoclonal, Mouse,IgG
稀释比例
WB: 1/500 - 1/2000
纯化工艺
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
浓度
1 mg/ml
储存
-20°C/1 year
其他名称
PPHLN1; HSPC206; HSPC232; Periphilin-1; Gastric cancer antigen Ga50
背景
The protein encoded by this gene is one of the several proteins that become sequentially incorporated into the cornified cell envelope during the terminal differentiation of keratinocyte at the outer layers of epidermis. This protein interacts with periplakin, which is known as a precursor of the cornified cell envelope. The cellular localization pattern and insolubility of this protein suggest that it may play a role in epithelial differentiation and contribute to epidermal integrity and barrier formation. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008],
功能
function:Involved in epithelial differentiation and contributes to epidermal integrity and barrier formation.,PTM:Substrate of transglutaminase (in vitro).,subcellular location:In undifferentiated keratinocytes expressed in speckle-type nuclear granules and at the nuclear membrane, but in the differentiated keratinocytes colocalized with periplakin at the cell periphery and at cell-cell junctions.,subunit:Homodimer. Interacts with PPL.,tissue specificity:Ubiquitous.,

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