免疫原
The antiserum was produced against synthesized peptide derived from human Ameloblastin. AA range:275-324
特异性
Ameloblastin Monoclonal Antibody detects endogenous levels of Ameloblastin protein.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
Western Blot: 1/500 - 1/2000
纯化工艺
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
背景
This gene encodes the nonamelogenin enamel matrix protein ameloblastin. The encoded protein may be important in enamel matrix formation and mineralization. This gene is located in the calcium-binding phosphoprotein gene cluster on chromosome 4. Mutations in this gene may be associated with dentinogenesis imperfect and autosomal dominant amylogenesis imperfect. [provided by RefSeq, Aug 2011],
功能
disease:Defects in AMBN are found in patients with ameloblastomas.,function:Involved in the mineralization and structural organization of enamel.,similarity:Belongs to the ameloblastin family.,tissue specificity:Ameloblast-specific. Located at the Tomes processes of secretory ameloblasts and in the sheath space between rod-interrod enamel.,
