免疫原
The antiserum was produced against synthesized peptide derived from human UBQLN3. AA range:271-320
特异性
Ubiquilin-3 Monoclonal Antibody detects endogenous levels of Ubiquilin-3 protein.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
背景
Summary: This gene encodes an ubiquitin-like protein (ubiquilin) that shares high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain a N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases, and thus thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation. This gene is specifically expressed in the testis, and proposed to regulate cell-cycle progression during spermatogenesis. [provided by RefSeq, Jul 2008],
功能
similarity:Contains 1 UBA domain.,similarity:Contains 1 ubiquitin-like domain.,tissue specificity:Testis specific.,
