蛋白名称
Tyrosine 3-monooxygenase
免疫原
The antiserum was produced against synthesized peptide derived from human Tyrosine Hydroxylase. AA range:5-54
特异性
TH Monoclonal Antibody detects endogenous levels of TH protein.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
其他名称
TH; TYH; Tyrosine 3-monooxygenase; Tyrosine 3-hydroxylase; TH
背景
Tyrosine 3-monooxygenase encoded by TH is involved in the conversion of tyrosine to dopamine. It is the rate-limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons. Mutations in this gene have be associated with autosomal recessive Segawa syndrome. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
