蛋白名称
Ubiquitin thioesterase OTUB2
免疫原
The antiserum was produced against synthesized peptide derived from human OTUB2. AA range:133-182
特异性
OTUB2 Monoclonal Antibody detects endogenous levels of OTUB2 protein.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
其他名称
OTUB2; C14orf137; OTB2; OTU2; Ubiquitin thioesterase OTUB2; Deubiquitinating enzyme OTUB2; OTU domain-containing ubiquitin aldehyde-binding protein 2; Otubain-2; Ubiquitin-specific-processing protease OTUB2
背景
OTU deubiquitinase, ubiquitin aldehyde binding 2(OTUB2) Homo sapiens This gene encodes one of several deubiquitylating enzymes. Ubiquitin modification of proteins is needed for their stability and function; to reverse the process, deubiquityling enzymes remove ubiquitin. This protein contains an OTU domain and binds Ubal (ubiquitin aldehyde); an active cysteine protease site is present in the OTU domain. [provided by RefSeq, Aug 2011],
功能
function:Hydrolase that can remove conjugated ubiquitin from proteins in vitro and may therefore play an important regulatory role at the level of protein turnover by preventing degradation.,similarity:Belongs to the peptidase C65 family.,similarity:Contains 1 OTU domain.,tissue specificity:Widely expressed. Expressed at higher level in brain.,
