背景
NEURL1B (neuralized homolog 1B), also known as neur2 or NEURL3, is a 555 amino acid protein that functions as an E3 ubiquitin-protein ligase. Involved in protein ubiquitination, NEURL1B contains two NHR (neuralized homology repeat) domains and one RING-type zinc finger. NEURL4 (neuralized homolog 4 (Drosophila)), also known as neuralized-like protein 4, is a 1,562 amino acid protein that is highly expressed in a wide variety of tissues. Containing six NHR (neuralized homology repeat) domains, NEURL4 exists as two alternatively spliced isoforms that are encoded by a gene that maps to human chromosome 17p13.1.
功能
microtubule cytoskeleton organization, microtubule bundle formation, reproductive developmental process, cell motion,cytoskeleton organization, microtubule-based process, gamete generation, germ cell development, spermatogenesis,spermatid development, sperm axoneme assembly, lactation, flagellum assembly, cellular component assembly involved in morphogenesis, sexual reproduction, cell projection organization, cell projection assembly, sperm motility,mammary gland development, multicellular organism reproduction, cellular component morphogenesis, axoneme assembly, flagellar axoneme assembly, flagellum organization, male gamete generation, spermatid differentiation,reproductive process in a multicellular organism, reproductive cellular process, gland development, cell motility,localization of cell,
