蛋白名称
NEDD4 family-interacting protein 1
免疫原
Synthesized peptide derived from Ndfip1 . at AA range: 150-230
特异性
Ndfip1 Monoclonal Antibody detects endogenous levels of Ndfip1 protein.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
Western Blot: 1/500 - 1/2000
纯化工艺
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
其他名称
NDFIP1; N4WBP5; PSEC0192; PSEC0223; NEDD4 family-interacting protein 1; Breast cancer-associated protein SGA-1M; NEDD4 WW domain-binding protein 5; Putative MAPK-activating protein PM13; Putative NF-kappa-B-activating protein 164; Putative
背景
The protein encoded by this gene belongs to a small group of evolutionarily conserved proteins with three transmembrane domains. It is a potential target for ubiquitination by the Nedd4 family of proteins. This protein is thought to be part of a family of integral Golgi membrane proteins. [provided by RefSeq, Jul 2008],
功能
developmental stage:Expressed in fetal brain, kidney and lung.,domain:The WW-binding motifs mediate interaction with NEDD4.,function:May play a role in Golgi structure maintenance.,PTM:Ubiquitinated by NEDD4; mono-, di- and polyubiquitinated forms are detected. Ubiquitination regulates its degradation.,subunit:Interacts with NEDD4. Interacts in vitro with NEDD4L, SR140, WWP2 and ITCH.,tissue specificity:Widely expressed. Higher levels are detected in cerebellum, pituitary, thalamus, kidney, liver, testis, salivary glands and placenta.,
