免疫原
The antiserum was produced against synthesized peptide derived from human Cytochrome P450 2S1. AA range:181-230
特异性
CYP2S1 Monoclonal Antibody detects endogenous levels of CYP2S1 protein.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
Western Blot: 1/500 - 1/2000
纯化工艺
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
其他名称
CYP2S1; Cytochrome P450 2S1; CYPIIS1
背景
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. In rodents, the homologous protein has been shown to metabolize certain carcinogens; however, the specific function of the human protein has not been determined. [provided by RefSeq, Jul 2008],
功能
catalytic activity:RH + reduced flavoprotein + O(2) = ROH + oxidized flavoprotein + H(2)O.,cofactor:Heme group.,function:Has a potential importance for extrahepatic xenobiotic metabolism.,similarity:Belongs to the cytochrome P450 family.,tissue specificity:High level of expression in trachea, lung, stomach, small intestine, and spleen.,
