蛋白名称
Cytosolic phospholipase A2 gamma
免疫原
The antiserum was produced against synthesized peptide derived from human PLA2G4C. AA range:301-350
特异性
cPLA2-γ Monoclonal Antibody detects endogenous levels of cPLA2-γ protein.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
Western Blot: 1/500 - 1/2000
纯化工艺
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
其他名称
PLA2G4C; Cytosolic phospholipase A2 gamma; cPLA2-gamma; Phospholipase A2 group IVC
背景
This gene encodes a protein which is a member of the phospholipase A2 enzyme family which hydrolyzes glycerophospholipids to produce free fatty acids and lysophospholipids, both of which serve as precursors in the production of signaling molecules. The encoded protein has been shown to be a calcium-independent and membrane bound enzyme. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2009],
功能
catalytic activity:Phosphatidylcholine + H(2)O = 1-acylglycerophosphocholine + a carboxylate.,enzyme regulation:Not regulated by calcium.,function:Has a preference for arachidonic acid at the sn-2 position of phosphatidylcholine as compared with palmitic acid.,similarity:Contains 1 PLA2c domain.,tissue specificity:Highly expressed in heart and skeletal muscle.,
