基因名称(Gene Name)
CTSB CPSB
蛋白名称
CATB (Cleaved-Asn126)
免疫原
Synthesized peptide derived from human CATB (Cleaved-Asn126)
特异性
This antibody detects endogenous levels of Human CATB (Cleaved-Asn126, protein was cleaved amino acid sequence between 126-127 )
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse serum by affinity-chromatography using specific immunogen.
其他名称
Cathepsin B (EC 3.4.22.1;APP secretase;APPS;Cathepsin B1) [Cleaved into: Cathepsin B light chain; Cathepsin B heavy chain]
背景
catalytic activity:Hydrolysis of proteins with broad specificity for peptide bonds. Preferentially cleaves -Arg-Arg-|-Xaa bonds in small molecule substrates (thus differing from cathepsin L). In addition to being an endopeptidase, shows peptidyl-dipeptidase activity, liberating C-terminal dipeptides.,function:Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Has also been implicated in tumor invasion and metastasis.,similarity:Belongs to the peptidase C1 family.,subcellular location:Identified by mass spectrometry in melanosome fractions from stage I to stage IV.,subunit:Dimer of a heavy chain and a light chain cross-linked by a disulfide bond.,
功能
proteolysis, response to wounding, regulation of cell death, regulation of apoptosis, regulation of programmed cell death,
