蛋白名称
Zinc finger protein 460
免疫原
The antiserum was produced against synthesized peptide derived from human ZNF460. AA range:461-510
特异性
ZNF460 Monoclonal Antibody detects endogenous levels of ZNF460 protein.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
Western Blot: 1/500 - 1/2000
纯化工艺
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
其他名称
ZNF460; ZNF272; Zinc finger protein 460; Zinc finger protein 272; Zinc finger protein HZF8
背景
zinc finger protein 460(ZNF460) Homo sapiens Zinc finger proteins, such as ZNF272, interact with nucleic acids and have diverse functions. The zinc finger domain is a conserved amino acid sequence motif containing 2 specifically positioned cysteines and 2 histidines that are involved in coordinating zinc. Kruppel-related proteins form 1 family of zinc finger proteins. See ZFP93 (MIM 604749) for additional information on zinc finger proteins.[supplied by OMIM, May 2004],
功能
function:May be involved in transcriptional regulation.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the krueppel C2H2-type zinc-finger protein family.,similarity:Contains 1 KRAB domain.,similarity:Contains 11 C2H2-type zinc fingers.,tissue specificity:Ubiquitously expressed at low levels. Highest levels are found in pancreas and liver.,
