蛋白名称
GC-rich sequence DNA-binding factor 2
免疫原
The antiserum was produced against synthesized peptide derived from human GCF. AA range:141-190
特异性
TCF-9 Monoclonal Antibody detects endogenous levels of TCF-9 protein.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
Western Blot: 1/500 - 1/2000
纯化工艺
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
其他名称
GCFC2; C2orf3; GCF; TCF9; GC-rich sequence DNA-binding factor 2; GC-rich sequence DNA-binding factor; Transcription factor 9; TCF-9
背景
The first mRNA transcript isolated for this gene was part of an artificial chimera derived from two distinct gene transcripts and a primer used in the cloning process (see Genbank accession M29204). A positively charged amino terminus present only in the chimera was determined to bind GC-rich DNA, thus mistakenly thought to identify a transcription factor gene. [provided by RefSeq, Jul 2008],
功能
function:Factor that represses transcription. It binds to the GC-rich sequences (5'-GCGGGGC-3') present in the epidermal growth factor receptor, beta-actin, and calcium-dependent protease promoters.,sequence caution:Contaminating sequence. The N-terminus matches the 2q37.3 region.,similarity:Belongs to the GCF family.,tissue specificity:Widely expressed in tissues and cell lines.,
