蛋白名称
Splicing factor suppressor of white-apricot homolog
免疫原
The antiserum was produced against synthesized peptide derived from human SFRS8. AA range:201-250
特异性
SWAP Monoclonal Antibody detects endogenous levels of SWAP protein.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
其他名称
SFSWAP; SFRS8; SWAP; Splicing factor; suppressor of white-apricot homolog; Splicing factor, arginine/serine-rich 8; Suppressor of white apricot protein homolog
背景
This gene encodes a human homolog of Drosophila splicing regulatory protein. This gene autoregulates its expression by control of splicing of its first two introns. In addition, it also regulates the splicing of fibronectin and CD45 genes. Two transcript variants encoding different isoforms have been identified. [provided by RefSeq, May 2012],
功能
function:May function as an alternative splicing regulator. Regulate its own expression at the level of RNA processing. Also regulates the splicing of fibronectin and CD45 genes. May act, at least in part, by interaction with other R/S-containing splicing factors.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 2 SURP motif repeats.,
