基因名称(Gene Name)
SOX8/9/17/18
蛋白名称
Transcription factor SOX-8/9/17/18
免疫原
The antiserum was produced against synthesized peptide derived from human SOX8/9/17/18. AA range:116-165
特异性
Sox-8/9/17/18 Monoclonal Antibody detects endogenous levels of Sox-8/9/17/18 protein.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
其他名称
SOX8; Transcription factor SOX-8; SOX9; Transcription factor SOX-9; SOX17; Transcription factor SOX-17; SOX18; Transcription factor SOX-18
背景
SRY-box 8(SOX8) Homo sapiens This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. This protein may be involved in brain development and function. Haploinsufficiency for this protein may contribute to the mental retardation found in haemoglobin H-related mental retardation (ART-16 syndrome). [provided by RefSeq, Jul 2008],
功能
function:May play a role in central nervous system, limb and facial development. May be involved in male sex determination. Binds the consensus motif 5'-[AT][AT]CAA[AT]G-3'.,similarity:Contains 1 HMG box DNA-binding domain.,
