反应种属
Human;Rat;Mouse;;Fish
蛋白名称
NFATC2-interacting protein
免疫原
The antiserum was produced against synthesized peptide derived from human NFATC2IP. AA range:151-200
特异性
NFATc2IP Monoclonal Antibody detects endogenous levels of NFATc2IP protein.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
其他名称
NFATC2IP; NIP45; NFATC2-interacting protein; 45 kDa NF-AT-interacting protein; 45 kDa NFAT-interacting protein; Nuclear factor of activated T-cells; cytoplasmic 2-interacting protein
背景
function:Plays a role in the inducible expression of cytokine genes in T-cells, especially by increasing NFAT-driven IL-4 production.,PTM:Methylation at the N-terminus by PRMT1 modulates interaction with the NFAT complex and results in augmented cytokine production.,similarity:Contains 1 ubiquitin-like domain.,subcellular location:TRAF1 is associated with a fraction of NFATC2IP in the cytoplasm and prevents its translocation to the nucleus.,subunit:Interacts with NFATC2, TRAF1, TRAF2 and PRMT1.,
功能
function:Plays a role in the inducible expression of cytokine genes in T-cells, especially by increasing NFAT-driven IL-4 production.,PTM:Methylation at the N-terminus by PRMT1 modulates interaction with the NFAT complex and results in augmented cytokine production.,similarity:Contains 1 ubiquitin-like domain.,subcellular location:TRAF1 is associated with a fraction of NFATC2IP in the cytoplasm and prevents its translocation to the nucleus.,subunit:Interacts with NFATC2, TRAF1, TRAF2 and PRMT1.,
