蛋白名称
Heat shock factor protein 2
免疫原
The antiserum was produced against synthesized peptide derived from human HSF2. AA range:401-450
特异性
HSF2 Monoclonal Antibody detects endogenous levels of HSF2 protein.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
其他名称
HSF2; HSTF2; Heat shock factor protein 2; HSF 2; Heat shock transcription factor 2; HSTF 2
背景
heat shock transcription factor 2(HSF2) Homo sapiens The protein encoded by this gene belongs to the HSF family of transcription factors that bind specifically to the heat-shock promoter element and activate transcription. Heat shock transcription factors activate heat-shock response genes under conditions of heat or other stresses. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2011],
功能
function:DNA-binding protein that specifically binds heat shock promoter elements (HSE) and activates transcription. In higher eukaryotes, HSF is unable to bind to the HSE unless the cells are heat shocked.,similarity:Belongs to the HSF family.,subcellular location:Cytoplasmic during normal growth and moves to the nucleus upon activation.,subunit:DNA-binding homotrimer in stressed or heat shocked cells, otherwise found as a homodimer.,
