蛋白名称
Forkhead box protein J1
免疫原
The antiserum was produced against synthesized peptide derived from human FOXJ1. AA range:271-320
特异性
FoxJ1 Monoclonal Antibody detects endogenous levels of FoxJ1 protein.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
其他名称
FOXJ1; FKHL13; HFH4; Forkhead box protein J1; Forkhead-related protein FKHL13; Hepatocyte nuclear factor 3 forkhead homolog 4; HFH-4
背景
This gene encodes a member of the forkhead family of transcription factors. Similar genes in zebrafish and mouse have been shown to regulate the transcription of genes that control the production of motile cilia. The mouse ortholog also functions in the determination of left-right asymmetry. Polymorphisms in this gene are associated with systemic lupus erythematosus and allergic rhinitis.[provided by RefSeq, Sep 2009],
功能
developmental stage:Expressed in developing lung, kidney and central nervous system.,disease:Genetic variations in FOXJ1 may be associated with susceptibility to allergic rhinitis (ALRH) [MIM:607154]. Allergic rhinitis is a common disease of complex inheritance and is characterized by mucosal inflammation caused by allergen exposure.,function:May play an important role in cell fate determination during lung development and in spermatogenesis.,similarity:Contains 1 fork-head DNA-binding domain.,tissue specificity:Testis, oviduct, lung and brain cortex.,
